What Changed

When the label changed, and what it said before

Read this first. An FDA label is revised for many reasons, and most of them are not safety findings — a manufacturer changes, a section is reformatted, a typographic correction is filed. A revision appearing here means the label document changed on the date shown. It does not by itself mean the drug became more dangerous, and this page never says that it did.

Where we can see which section changed, we say so. Where we cannot, we say that too rather than guessing. Nothing here is medical advice, and no entry is a reason to start or stop a medication on your own.

Every medication in our library is checked against the FDA’s own Structured Product Labels. We follow each drug by its label’s permanent document ID, so a revision recorded here is a change to that document, not a different company publishing its own copy of the same text. This record began on September 6, 2026, and was last checked on November 1, 2026.

  1. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected November 1, 2026. FDA Structured Product Label via openFDA and DailyMed

  2. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected November 1, 2026. FDA Structured Product Label via openFDA and DailyMed

  3. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 31, 2026. FDA Structured Product Label via openFDA and DailyMed

  4. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 30, 2026. FDA Structured Product Label via openFDA and DailyMed

  5. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 30, 2026. FDA Structured Product Label via openFDA and DailyMed

  6. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 29, 2026. FDA Structured Product Label via openFDA and DailyMed

  7. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 29, 2026. FDA Structured Product Label via openFDA and DailyMed

  8. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 28, 2026. FDA Structured Product Label via openFDA and DailyMed

  9. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 28, 2026. FDA Structured Product Label via openFDA and DailyMed

  10. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 27, 2026. FDA Structured Product Label via openFDA and DailyMed

  11. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 27, 2026. FDA Structured Product Label via openFDA and DailyMed

  12. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 26, 2026. FDA Structured Product Label via openFDA and DailyMed

  13. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 26, 2026. FDA Structured Product Label via openFDA and DailyMed

  14. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 25, 2026. FDA Structured Product Label via openFDA and DailyMed

  15. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 25, 2026. FDA Structured Product Label via openFDA and DailyMed

  16. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 24, 2026. FDA Structured Product Label via openFDA and DailyMed

  17. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 24, 2026. FDA Structured Product Label via openFDA and DailyMed

  18. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 23, 2026. FDA Structured Product Label via openFDA and DailyMed

  19. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 23, 2026. FDA Structured Product Label via openFDA and DailyMed

  20. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 22, 2026. FDA Structured Product Label via openFDA and DailyMed

  21. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 22, 2026. FDA Structured Product Label via openFDA and DailyMed

  22. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 21, 2026. FDA Structured Product Label via openFDA and DailyMed

  23. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 21, 2026. FDA Structured Product Label via openFDA and DailyMed

  24. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 20, 2026. FDA Structured Product Label via openFDA and DailyMed

  25. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 20, 2026. FDA Structured Product Label via openFDA and DailyMed

  26. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 19, 2026. FDA Structured Product Label via openFDA and DailyMed

  27. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 19, 2026. FDA Structured Product Label via openFDA and DailyMed

  28. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 18, 2026. FDA Structured Product Label via openFDA and DailyMed

  29. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 18, 2026. FDA Structured Product Label via openFDA and DailyMed

  30. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 16, 2026. FDA Structured Product Label via openFDA and DailyMed

  31. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 16, 2026. FDA Structured Product Label via openFDA and DailyMed

  32. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 15, 2026. FDA Structured Product Label via openFDA and DailyMed

  33. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 15, 2026. FDA Structured Product Label via openFDA and DailyMed

  34. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 14, 2026. FDA Structured Product Label via openFDA and DailyMed

  35. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 14, 2026. FDA Structured Product Label via openFDA and DailyMed

  36. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 13, 2026. FDA Structured Product Label via openFDA and DailyMed

  37. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 13, 2026. FDA Structured Product Label via openFDA and DailyMed

  38. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 12, 2026. FDA Structured Product Label via openFDA and DailyMed

  39. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 12, 2026. FDA Structured Product Label via openFDA and DailyMed

  40. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 11, 2026. FDA Structured Product Label via openFDA and DailyMed

  41. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 11, 2026. FDA Structured Product Label via openFDA and DailyMed

  42. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 10, 2026. FDA Structured Product Label via openFDA and DailyMed

  43. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 10, 2026. FDA Structured Product Label via openFDA and DailyMed

  44. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 9, 2026. FDA Structured Product Label via openFDA and DailyMed

  45. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 9, 2026. FDA Structured Product Label via openFDA and DailyMed

  46. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 8, 2026. FDA Structured Product Label via openFDA and DailyMed

  47. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 8, 2026. FDA Structured Product Label via openFDA and DailyMed

  48. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 7, 2026. FDA Structured Product Label via openFDA and DailyMed

  49. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 7, 2026. FDA Structured Product Label via openFDA and DailyMed

  50. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 6, 2026. FDA Structured Product Label via openFDA and DailyMed

  51. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 6, 2026. FDA Structured Product Label via openFDA and DailyMed

  52. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 5, 2026. FDA Structured Product Label via openFDA and DailyMed

  53. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 5, 2026. FDA Structured Product Label via openFDA and DailyMed

  54. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 4, 2026. FDA Structured Product Label via openFDA and DailyMed

  55. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 4, 2026. FDA Structured Product Label via openFDA and DailyMed

  56. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 3, 2026. FDA Structured Product Label via openFDA and DailyMed

  57. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 3, 2026. FDA Structured Product Label via openFDA and DailyMed

  58. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 2, 2026. FDA Structured Product Label via openFDA and DailyMed

  59. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 2, 2026. FDA Structured Product Label via openFDA and DailyMed

  60. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected October 1, 2026. FDA Structured Product Label via openFDA and DailyMed

  61. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected October 1, 2026. FDA Structured Product Label via openFDA and DailyMed

  62. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 30, 2026. FDA Structured Product Label via openFDA and DailyMed

  63. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 30, 2026. FDA Structured Product Label via openFDA and DailyMed

  64. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 28, 2026. FDA Structured Product Label via openFDA and DailyMed

  65. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 28, 2026. FDA Structured Product Label via openFDA and DailyMed

  66. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 27, 2026. FDA Structured Product Label via openFDA and DailyMed

  67. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 27, 2026. FDA Structured Product Label via openFDA and DailyMed

  68. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 26, 2026. FDA Structured Product Label via openFDA and DailyMed

  69. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 26, 2026. FDA Structured Product Label via openFDA and DailyMed

  70. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 25, 2026. FDA Structured Product Label via openFDA and DailyMed

  71. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 25, 2026. FDA Structured Product Label via openFDA and DailyMed

  72. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 24, 2026. FDA Structured Product Label via openFDA and DailyMed

  73. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 24, 2026. FDA Structured Product Label via openFDA and DailyMed

  74. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 23, 2026. FDA Structured Product Label via openFDA and DailyMed

  75. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 23, 2026. FDA Structured Product Label via openFDA and DailyMed

  76. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 22, 2026. FDA Structured Product Label via openFDA and DailyMed

  77. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 22, 2026. FDA Structured Product Label via openFDA and DailyMed

  78. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 21, 2026. FDA Structured Product Label via openFDA and DailyMed

  79. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 21, 2026. FDA Structured Product Label via openFDA and DailyMed

  80. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 20, 2026. FDA Structured Product Label via openFDA and DailyMed

  81. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 20, 2026. FDA Structured Product Label via openFDA and DailyMed

  82. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 19, 2026. FDA Structured Product Label via openFDA and DailyMed

  83. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 19, 2026. FDA Structured Product Label via openFDA and DailyMed

  84. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 18, 2026. FDA Structured Product Label via openFDA and DailyMed

  85. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 18, 2026. FDA Structured Product Label via openFDA and DailyMed

  86. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 17, 2026. FDA Structured Product Label via openFDA and DailyMed

  87. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 17, 2026. FDA Structured Product Label via openFDA and DailyMed

  88. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 16, 2026. FDA Structured Product Label via openFDA and DailyMed

  89. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 16, 2026. FDA Structured Product Label via openFDA and DailyMed

  90. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 15, 2026. FDA Structured Product Label via openFDA and DailyMed

  91. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 15, 2026. FDA Structured Product Label via openFDA and DailyMed

  92. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 14, 2026. FDA Structured Product Label via openFDA and DailyMed

  93. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 14, 2026. FDA Structured Product Label via openFDA and DailyMed

  94. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 13, 2026. FDA Structured Product Label via openFDA and DailyMed

  95. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 13, 2026. FDA Structured Product Label via openFDA and DailyMed

  96. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 12, 2026. FDA Structured Product Label via openFDA and DailyMed

  97. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 12, 2026. FDA Structured Product Label via openFDA and DailyMed

  98. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 11, 2026. FDA Structured Product Label via openFDA and DailyMed

  99. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 11, 2026. FDA Structured Product Label via openFDA and DailyMed

  100. lisdexamfetamine

    Effective August 11, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 24 → 25, previously effective August 28, 2026. Detected September 10, 2026. FDA Structured Product Label via openFDA and DailyMed

  101. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 10, 2026. FDA Structured Product Label via openFDA and DailyMed

  102. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 9, 2026. FDA Structured Product Label via openFDA and DailyMed

  103. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 8, 2026. FDA Structured Product Label via openFDA and DailyMed

  104. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 7, 2026. FDA Structured Product Label via openFDA and DailyMed

  105. trazodone

    Effective September 1, 2026

    • The boxed warning text changed.
    • The drug interactions section changed.

    Label document version 5 → 6, previously effective August 27, 2026. Detected September 6, 2026. FDA Structured Product Label via openFDA and DailyMed

How this is built

Drug labels in the United States are filed as Structured Product Labels, and each one carries a permanent document ID and a version number that increments when the labeler files a revision. We store the version we last saw for every medication in our library and compare it against the FDA’s current one. When it moves, the change is recorded here with the date the new label took effect and a link to the document itself, so you can read it rather than take our word for it.

One honest limit: the FDA publishes the current label, not a diff. We can tell you a section changed and when, and we can link you to what it says now. We cannot show you the removed wording unless we happened to be watching before it went.

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