The library
Everything we publish, in one place. Every claim on every page cites a named primary source; where the honest answer is an absence, the absence is printed rather than filled in.
medications A–Z
37 medications — each page carries the FDA approval journey with label quotes, safety signals with the caveats above the numbers, and who pays for prescriptions (Medicare, Medicaid, and the commercial absence).
- alprazolam
- amphetamine
- aripiprazole
- atomoxetine
- buprenorphine
- bupropion
- buspirone
- citalopram
- clonazepam
- desvenlafaxine
- diazepam
- duloxetine
- escitalopram
- esketamine
- fluoxetine
- gabapentin
- guanfacine
- hydroxyzine
- lamotrigine
- lisdexamfetamine
- lithium
- lorazepam
- lurasidone
- methylphenidate
- mirtazapine
- modafinil
- olanzapine
- paroxetine
- quetiapine
- risperidone
- sertraline
- temazepam
- trazodone
- venlafaxine
- vortioxetine
- ziprasidone
- zolpidem
supplements & unapproved substances
17 substances people buy without a prescription. Each page leads with the verbatim regulatory paragraph (sold under DSHEA, never reviewed for effectiveness, dose in the capsule unverified, approved for nothing), then the studies, then the risks, then what the research does not cover. Where the honest finding is futility rather than danger, the page says so.
- 5-HTP — What the trials show, and the serotonergic interactions that make it a pharmacist question
- Ashwagandha — The anxiety and stress trials, and the liver-injury reports
- Cannabidiol (CBD) — The anxiety evidence, the dose gap, and the liver signal
- Cannabis and THC — What the controlled evidence shows, separated from the policy argument
- Creatine — The depression syntheses, and why a raised creatinine reading is not kidney damage
- Kratom — Opioid pharmacology, dependence, and what the human evidence actually is
- L-Theanine — Nine small trials, none in a diagnosed anxiety disorder, and one null pooled estimate
- Magnesium — What the trials measured, and what deficiency correction does and does not tell you
- Melatonin — The sleep evidence, and how much melatonin is actually in the bottle
- Methylene Blue — An MAO-A inhibitor sold as a nootropic, and the serotonin-syndrome record
- Microdosing — Where placebo control is enforced, most of the benefit disappears
- N-Acetylcysteine (NAC) — The psychiatric trials, by condition, and where the pooled estimates land
- Omega-3 — The depression meta-analyses, the EPA/DHA split, and the heterogeneity problem
- Phenibut — Dependence and withdrawal, from the case record
- SAMe — The depression trials, and the mania and interaction signals
- St John’s Wort — The depression trials, and the interaction list that makes it dangerous with other drugs
- Valerian — A good safety record and an unconvincing efficacy record
Compared, side by side
33 head-to-head pages for the pairs people actually search — comparing the public record only (usage, payers, warnings, litigation), never ranking.
- escitalopram vs sertraline
- fluoxetine vs sertraline
- citalopram vs escitalopram
- citalopram vs sertraline
- escitalopram vs fluoxetine
- fluoxetine vs paroxetine
- bupropion vs sertraline
- bupropion vs escitalopram
- bupropion vs fluoxetine
- duloxetine vs venlafaxine
- sertraline vs venlafaxine
- duloxetine vs sertraline
- desvenlafaxine vs venlafaxine
- escitalopram vs vortioxetine
- mirtazapine vs trazodone
- mirtazapine vs sertraline
- buspirone vs hydroxyzine
- alprazolam vs clonazepam
- alprazolam vs lorazepam
- clonazepam vs diazepam
- alprazolam vs hydroxyzine
- trazodone vs zolpidem
- temazepam vs zolpidem
- amphetamine vs methylphenidate
- amphetamine vs lisdexamfetamine
- atomoxetine vs methylphenidate
- atomoxetine vs guanfacine
- olanzapine vs quetiapine
- aripiprazole vs risperidone
- aripiprazole vs quetiapine
- olanzapine vs risperidone
- lurasidone vs quetiapine
- lamotrigine vs lithium
legal & safety records
The litigation and recall record per drug, stated precisely: settled is never adjudicated, verdicts carry their reductions, and verified negatives state their coverage window.
the system, counted
How the headline numbers of mental health are actually produced — prevalence, trial durations, diagnosis counts — with every method break annotated.
- How many adults take psychiatric medication? — Every federal number with its definition attached
- How autism got counted — Every method break annotated in CDC’s own words
- How childhood ADHD got counted
- How long psychiatric drugs were tested — Every study horizon in the library, counted
- The longest trial behind each approval — Trial weeks beside patient counts, drug by drug
- LGBTQ+ mental health in the data
- The DSM: the book, the money, the count
- What the DSM is for
- The mental health lexicon — Nineteen terms where usage outran evidence
- Two numbers nobody measured — Two statistics about psychiatric medication and violence, traced to their sources
follow the money
Who funds the research, the education, the advocacy, and the coverage — from federal filings and the organizations’ own disclosures. Payments are facts, not verdicts; the framing travels with every number.
- How your doctor gets paid — Look up any US physician’s industry payments
- Who funds psychiatric drug research
- Who funds doctors’ education
- Who funds mental health advocacy
- Who funds the nonprofits
- Pharma and the news
- How pharma makes and spends money — Revenue, R&D, SG&A and psychiatric drug sales, from the 10-Ks
- What is a PBM? — The middlemen between your prescription and its price
- Who profits from US health care — Six sectors, ten years, 28 named SEC filers — margins and growth against CPI
- Where the money goes — US health spending, prices and named-basket profits as time series, 1960 to today
- What changed — A dated record of FDA label revisions to the medications we cover, checked daily
- Who funds veisund — The question we ask of everyone else, answered about ourselves
health questions, answered from primaries
The questions people actually search, answered from trials, labels, and regulators — including the ones where the honest answer is “the evidence is thin.”
- Do any supplements actually work?
- Does ashwagandha work for anxiety?
- Does CBD help anxiety?
- St John’s wort: the interaction list
- Is kratom dangerous?
- SSRI sexual side effects
- Ketamine vs esketamine: FDA status
- Psychedelic therapy: the FDA status table
- AI mental health tools: FDA status
- What each medication is approved FOR
- Postpartum depression: the evidence
- Depression & anxiety in pregnancy
- Depression and trauma after miscarriage
- Does infertility cause depression?
- Sex, fertility, and mental health
- Male loneliness: what actually moves it
- AI vs human support
glossary
34 plain-English definitions — the vocabulary needed to read medication evidence and litigation coverage precisely, each with a worked example from this site’s own record.
- Peer support
- Emotional support
- Support group
- Active listening
- Social isolation
- Co-regulation
- Mutual aid
- Anonymous support
- Boxed warning (black box warning)
- Off-label use
- Discontinuation syndrome
- Half-life
- Pivotal trial
- Open-label extension
- Effect size
- Number needed to treat (NNT)
- Placebo response
- FAERS (FDA adverse event reporting system)
- Bioequivalence
- Recall classes (class I, II, III)
- MDL (multidistrict litigation)
- Bellwether trial
- Settled vs. adjudicated
- Dual-eligible (medicare under 65)
- Pay-for-delay
- REMS (risk evaluation and mitigation strategy)
- Relative vs absolute risk
- Intention-to-treat vs per-protocol
- Wait-list control
- Warning letter (FDA)
- Complete response letter (CRL)
- Sentinel surveillance
- Survey response rate
- Confidence interval
tools
Interactive, free, and no email required.
- How your doctor gets paid — Open Payments lookup with company pivots
- How long were they tested before approval? — The pivotal trials behind all 37 medications — weeks, people, comparator, NDA
- Side-effect rates, drug vs placebo — The label’s own adverse-reaction table for all 37 medications
- Therapy cost calculator — Per month and per year — in-person, online, insurance, sliding scale
- Sliding-scale checker — Household size and income against the 2026 federal poverty guidelines
- What do you actually need? — Six questions, no email
the evidence library
Every study behind the pages above, individually summarized and scored for trust — design, funding, venue, sample size, preregistration.
Browse the scored evidence library → — or start from the blog and our experts.